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Exercise protects against doxorubicin-induced oxidative stress and proteolysis in skeletal muscle

Doxorubicin (Dox) is a potent antitumor agent used in cancer treatment. Unfortunately, Dox is myotoxic and results in significant reductions in skeletal muscle mass and function. Complete knowledge of the mechanism(s) by which Dox induces toxicity in skeletal muscle is incomplete, but it is establis...

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Bibliografiske detaljer
Main Authors: Smuder, Ashley J., Kavazis, Andreas N., Min, Kisuk, Powers, Scott K.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075128/
https://ncbi.nlm.nih.gov/pubmed/21310889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00677.2010
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