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Effects of doxorubicin on cardiac muscle subsarcolemmal and intermyofibrillar mitochondria
Doxorubicin (DOX) is a highly effective chemotherapeutic used in the treatment of a broad spectrum of malignancies. However, clinical use of DOX is highly limited by cumulative and irreversible cardiomyopathy that occurs following DOX treatment. The pathogenesis of DOX-induced cardiac muscle dysfunc...
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Publicado no: | Mitochondrion |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422146/ https://ncbi.nlm.nih.gov/pubmed/27832997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2016.10.008 |
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