Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning

Doxorubicin (DOX) is a highly effective anthracycline antibiotic. Unfortunately, the clinical use of DOX is limited by the risk of deleterious effects to cardiac and respiratory (i.e. diaphragm) muscle, resulting from mitochondrial reactive oxygen species (ROS) production. In this regard, exercise i...

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Vydáno v:Mitochondrion
Hlavní autoři: Morton, Aaron B., Mor, Andres, Hinkley, J. Matthew, Ichinoseki-Sekine, Noriko, Christou, Demetra D., Smuder, Ashley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103903/
https://ncbi.nlm.nih.gov/pubmed/29474837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2018.02.005
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