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Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning
Doxorubicin (DOX) is a highly effective anthracycline antibiotic. Unfortunately, the clinical use of DOX is limited by the risk of deleterious effects to cardiac and respiratory (i.e. diaphragm) muscle, resulting from mitochondrial reactive oxygen species (ROS) production. In this regard, exercise i...
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| Veröffentlicht in: | Mitochondrion |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6103903/ https://ncbi.nlm.nih.gov/pubmed/29474837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2018.02.005 |
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