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Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning

Doxorubicin (DOX) is a highly effective anthracycline antibiotic. Unfortunately, the clinical use of DOX is limited by the risk of deleterious effects to cardiac and respiratory (i.e. diaphragm) muscle, resulting from mitochondrial reactive oxygen species (ROS) production. In this regard, exercise i...

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Dettagli Bibliografici
Pubblicato in:Mitochondrion
Autori principali: Morton, Aaron B., Mor, Andres, Hinkley, J. Matthew, Ichinoseki-Sekine, Noriko, Christou, Demetra D., Smuder, Ashley J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103903/
https://ncbi.nlm.nih.gov/pubmed/29474837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2018.02.005
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