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Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning

Doxorubicin (DOX) is a highly effective anthracycline antibiotic. Unfortunately, the clinical use of DOX is limited by the risk of deleterious effects to cardiac and respiratory (i.e. diaphragm) muscle, resulting from mitochondrial reactive oxygen species (ROS) production. In this regard, exercise i...

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Detalhes bibliográficos
Publicado no:Mitochondrion
Main Authors: Morton, Aaron B., Mor, Andres, Hinkley, J. Matthew, Ichinoseki-Sekine, Noriko, Christou, Demetra D., Smuder, Ashley J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103903/
https://ncbi.nlm.nih.gov/pubmed/29474837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2018.02.005
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