Skeletal Muscle Mitochondria in Insulin Resistance: Differences in Intermyofibrillar Versus Subsarcolemmal Subpopulations and Relationship to Metabolic Flexibility

CONTEXT: Insulin resistance is accompanied by lower lipid oxidation during fasting and metabolic inflexibility. Whether these abnormalities correlate with mitochondrial content in skeletal muscle is unknown. OBJECTIVE: The objective of the study was to investigate whether decreased fasting lipid oxi...

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Hlavní autoři: Chomentowski, Peter, Coen, Paul M., Radiková, Zofia, Goodpaster, Bret H., Toledo, Frederico G. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Endocrine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048328/
https://ncbi.nlm.nih.gov/pubmed/21106709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0822
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