Both tails and the centromere targeting domain of CENP-A are required for centromere establishment

The centromere—defined by the presence of nucleosomes containing the histone H3 variant, CENP-A—is the chromosomal locus required for the accurate segregation of chromosomes during cell division. Although the sequence determinants of human CENP-A required to maintain a centromere were reported, thos...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Logsdon, Glennis A., Barrey, Evelyne J., Bassett, Emily A., DeNizio, Jamie E., Guo, Lucie Y., Panchenko, Tanya, Dawicki-McKenna, Jennine M., Heun, Patrick, Black, Ben E.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347640/
https://ncbi.nlm.nih.gov/pubmed/25713413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412011
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