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Cytokines reinstate NK cell–mediated cancer immunosurveillance
In healthy individuals, cells that lose expression of MHC class I molecules are quickly targeted for elimination by NK lymphocytes. A paradox in cancer immunology is the observation that many tumor cells often have a drastic reduction of MHC class I molecules, yet these cells are not eliminated by N...
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| Published in: | J Clin Invest |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347239/ https://ncbi.nlm.nih.gov/pubmed/25329691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78531 |
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