Positive impact of autophagy in human breast cancer cells on local immunosurveillance

In human breast cancer cells, the presence of cytoplasmic dots positive for microtubule-associated proteins 1A/1B light chain 3B (LC3B) indicates enhanced autophagic flux and favorable prognosis. LC3B(+) puncta within malignant cells positively correlate with the intratumoral abundance of CD8(+) cyt...

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Publicat a:Oncoimmunology
Autors principals: Ladoire, Sylvain, Enot, David, Senovilla, Laura, Chaix, Marie, Zitvogel, Laurence, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938361/
https://ncbi.nlm.nih.gov/pubmed/27471653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1174801
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