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Failure of immunosurveillance accelerates aging

Immunosurveillance is generally conceived as a mechanism through which the immune system detects and eliminates (pre-)malignant cells, thus reducing the risk of developing cancer. A recent paper by Ovadya et al. demonstrates that knockout of the gene coding for perforin-1 causes accelerated accumula...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Perez-Lanzon, Maria, Zitvogel, Laurence, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422365/
https://ncbi.nlm.nih.gov/pubmed/30906669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1575117
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