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RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis
Osteoclastogenesis requires activation of RANK signaling as well as costimulatory signals from immunoreceptor tyrosine-based activation motif-containing (ITAM-containing) receptors/adaptors, predominantly tyrosine kinase–binding proteins DAP12 and FcRγ, in osteoclast precursors. It is not well under...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347236/ https://ncbi.nlm.nih.gov/pubmed/25329696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71882 |
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