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RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes
Development of alternatively activated (M2) macrophage phenotypes is a complex process that is coordinately regulated by a plethora of pathways and factors. Here, we report that RBP-J, a DNA-binding protein that integrates signals from multiple pathways including the Notch pathway, is critically inv...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791428/ https://ncbi.nlm.nih.gov/pubmed/26874522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0248-7 |
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