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TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J

Tumor necrosis factor (TNF) plays a key role in the pathogenesis of inflammatory bone resorption and associated morbidity in diseases such as rheumatoid arthritis and periodontitis. Mechanisms that regulate the direct osteoclastogenic properties of TNF to limit pathological bone resorption in inflam...

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Detalhes bibliográficos
Main Authors: Zhao, Baohong, Grimes, Shannon N., Li, Susan, Hu, Xiaoyu, Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280875/
https://ncbi.nlm.nih.gov/pubmed/22249448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111566
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