Skin exposure promotes a Th2-dependent sensitization to peanut allergens

Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy. Here, we tested the hypothesis that peanut proteins activate innate immune pathways in the skin that promote sensitization. We exposed mice to...

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發表在:J Clin Invest
Main Authors: Tordesillas, Leticia, Goswami, Ritobrata, Benedé, Sara, Grishina, Galina, Dunkin, David, Järvinen, Kirsi M., Maleki, Soheila J., Sampson, Hugh A., Berin, M. Cecilia
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2014
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347216/
https://ncbi.nlm.nih.gov/pubmed/25295541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75660
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