Skin exposure promotes a Th2-dependent sensitization to peanut allergens

Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy. Here, we tested the hypothesis that peanut proteins activate innate immune pathways in the skin that promote sensitization. We exposed mice to...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Tordesillas, Leticia, Goswami, Ritobrata, Benedé, Sara, Grishina, Galina, Dunkin, David, Järvinen, Kirsi M., Maleki, Soheila J., Sampson, Hugh A., Berin, M. Cecilia
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347216/
https://ncbi.nlm.nih.gov/pubmed/25295541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75660
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