Skin exposure promotes a Th2-dependent sensitization to peanut allergens

Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy. Here, we tested the hypothesis that peanut proteins activate innate immune pathways in the skin that promote sensitization. We exposed mice to...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Tordesillas, Leticia, Goswami, Ritobrata, Benedé, Sara, Grishina, Galina, Dunkin, David, Järvinen, Kirsi M., Maleki, Soheila J., Sampson, Hugh A., Berin, M. Cecilia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347216/
https://ncbi.nlm.nih.gov/pubmed/25295541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75660
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