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Skin exposure promotes a Th2-dependent sensitization to peanut allergens

Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy. Here, we tested the hypothesis that peanut proteins activate innate immune pathways in the skin that promote sensitization. We exposed mice to...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tordesillas, Leticia, Goswami, Ritobrata, Benedé, Sara, Grishina, Galina, Dunkin, David, Järvinen, Kirsi M., Maleki, Soheila J., Sampson, Hugh A., Berin, M. Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347216/
https://ncbi.nlm.nih.gov/pubmed/25295541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75660
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