Skin exposure promotes a Th2-dependent sensitization to peanut allergens

Sensitization to foods often occurs in infancy, without a known prior oral exposure, suggesting that alternative exposure routes contribute to food allergy. Here, we tested the hypothesis that peanut proteins activate innate immune pathways in the skin that promote sensitization. We exposed mice to...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Tordesillas, Leticia, Goswami, Ritobrata, Benedé, Sara, Grishina, Galina, Dunkin, David, Järvinen, Kirsi M., Maleki, Soheila J., Sampson, Hugh A., Berin, M. Cecilia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347216/
https://ncbi.nlm.nih.gov/pubmed/25295541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75660
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