Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle

Anticancer treatments for childhood acute lymphoblastic leukaemia (ALL) are highly effective but are now implicated in causing impaired muscle function in long-term survivors. However, no comprehensive assessment of skeletal muscle mitochondrial functions in long-term survivors has been performed an...

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Pubblicato in:Sci Rep
Autori principali: Gouspillou, Gilles, Scheede-Bergdahl, Celena, Spendiff, Sally, Vuda, Madhusudanarao, Meehan, Brian, Mlynarski, Heather, Archer-Lahlou, Elodie, Sgarioto, Nicolas, Purves-Smith, Fennigje M., Konokhova, Yana, Rak, Janusz, Chevalier, Stéphanie, Taivassalo, Tanja, Hepple, Russell T., Jagoe, R. Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346812/
https://ncbi.nlm.nih.gov/pubmed/25732599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08717
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