Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle

Anticancer treatments for childhood acute lymphoblastic leukaemia (ALL) are highly effective but are now implicated in causing impaired muscle function in long-term survivors. However, no comprehensive assessment of skeletal muscle mitochondrial functions in long-term survivors has been performed an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gouspillou, Gilles, Scheede-Bergdahl, Celena, Spendiff, Sally, Vuda, Madhusudanarao, Meehan, Brian, Mlynarski, Heather, Archer-Lahlou, Elodie, Sgarioto, Nicolas, Purves-Smith, Fennigje M., Konokhova, Yana, Rak, Janusz, Chevalier, Stéphanie, Taivassalo, Tanja, Hepple, Russell T., Jagoe, R. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346812/
https://ncbi.nlm.nih.gov/pubmed/25732599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08717
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