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Dual regulation of tumor necrosis factor-α on myosin light chain phosphorylation in vascular smooth muscle
We previously demonstrated that inhibitor κB kinase 2 (IKK2) is a myosin light chain kinase (MLCK). In the present study, we assess whether the prototypical activator of IKK2 tumor necrosis factor-α (TNF-α) regulates the MLCK activity of IKK2 and thus MLC phosphorylation in vascular smooth muscle ce...
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出版年: | Am J Physiol Heart Circ Physiol |
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主要な著者: | , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
American Physiological Society
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346769/ https://ncbi.nlm.nih.gov/pubmed/25502110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00691.2014 |
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