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Dual regulation of tumor necrosis factor-α on myosin light chain phosphorylation in vascular smooth muscle

We previously demonstrated that inhibitor κB kinase 2 (IKK2) is a myosin light chain kinase (MLCK). In the present study, we assess whether the prototypical activator of IKK2 tumor necrosis factor-α (TNF-α) regulates the MLCK activity of IKK2 and thus MLC phosphorylation in vascular smooth muscle ce...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Chen, Minjie, Ma, Lan, Hall, John E., Liu, Xuebo, Ying, Zhekang
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346769/
https://ncbi.nlm.nih.gov/pubmed/25502110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00691.2014
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