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Endogenous flow-induced nitric oxide reduces superoxide-stimulated Na/H exchange activity via PKG in thick ascending limbs

Luminal flow stimulates endogenous nitric oxide (NO) and superoxide (O(2)(−)) production by renal thick ascending limbs (TALs). The delicate balance between these two factors regulates Na transport in TALs; NO enhances natriuresis, whereas O(2)(−) augments Na absorption. Endogenous, flow-stimulated...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Hong, Nancy J., Garvin, Jeffrey L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346749/
https://ncbi.nlm.nih.gov/pubmed/25503735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00583.2014
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