Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease Is Reversed by IFN-γ in a Nitric Oxide-Dependent Manner

Immunodeficiency in chronic granulomatous disease (CGD) is well characterized. Less understood are exaggerated sterile inflammation and autoimmunity associated with CGD. Impaired recognition and clearance of apoptotic cells resulting in their disintegration may contribute to CGD inflammation. We hyp...

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Publicado no:J Immunol
Main Authors: Fernandez-Boyanapalli, Ruby, McPhillips, Kathleen A., Frasch, S. Courtney, Janssen, William J., Dinauer, Mary C., Riches, David W. H., Henson, Peter M., Byrne, Aideen, Bratton, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346245/
https://ncbi.nlm.nih.gov/pubmed/20805415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001778
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