PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease

Absence of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase predisposes chronic granulomatous disease (CGD) patients to infection, and also to unexplained, exaggerated inflammation. The impaired recognition and removal (efferocytosis) of apoptotic neutrophils by CGD macrophag...

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Detalhes bibliográficos
Main Authors: Fernandez-Boyanapalli, Ruby, Frasch, S. Courtney, Riches, David W. H., Vandivier, R. William, Henson, Peter M., Bratton, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996113/
https://ncbi.nlm.nih.gov/pubmed/20693431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-272005
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