PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease

Absence of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase predisposes chronic granulomatous disease (CGD) patients to infection, and also to unexplained, exaggerated inflammation. The impaired recognition and removal (efferocytosis) of apoptotic neutrophils by CGD macrophag...

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Détails bibliographiques
Auteurs principaux: Fernandez-Boyanapalli, Ruby, Frasch, S. Courtney, Riches, David W. H., Vandivier, R. William, Henson, Peter M., Bratton, Donna L.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2010
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996113/
https://ncbi.nlm.nih.gov/pubmed/20693431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-272005
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