PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease

Absence of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase predisposes chronic granulomatous disease (CGD) patients to infection, and also to unexplained, exaggerated inflammation. The impaired recognition and removal (efferocytosis) of apoptotic neutrophils by CGD macrophag...

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Bibliographische Detailangaben
Hauptverfasser: Fernandez-Boyanapalli, Ruby, Frasch, S. Courtney, Riches, David W. H., Vandivier, R. William, Henson, Peter M., Bratton, Donna L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996113/
https://ncbi.nlm.nih.gov/pubmed/20693431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-272005
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