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PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease
Absence of a functional nicotinamide adenine dinucleotide phosphate (NADPH) oxidase predisposes chronic granulomatous disease (CGD) patients to infection, and also to unexplained, exaggerated inflammation. The impaired recognition and removal (efferocytosis) of apoptotic neutrophils by CGD macrophag...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996113/ https://ncbi.nlm.nih.gov/pubmed/20693431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-272005 |
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