Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes

Tandemly repeated ribosomal DNA (rDNA) arrays are among the most evolutionary dynamic loci of eukaryotic genomes. The loci code for essential cellular components, yet exhibit extensive copy number (CN) variation within and between species. CN might be partly determined by the requirement of dosage b...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gibbons, John G., Branco, Alan T., Godinho, Susana A., Yu, Shoukai, Lemos, Bernardo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345604/
https://ncbi.nlm.nih.gov/pubmed/25583482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416878112
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