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Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes
Tandemly repeated ribosomal DNA (rDNA) arrays are among the most evolutionary dynamic loci of eukaryotic genomes. The loci code for essential cellular components, yet exhibit extensive copy number (CN) variation within and between species. CN might be partly determined by the requirement of dosage b...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345604/ https://ncbi.nlm.nih.gov/pubmed/25583482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416878112 |
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