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Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes

Tandemly repeated ribosomal DNA (rDNA) arrays are among the most evolutionary dynamic loci of eukaryotic genomes. The loci code for essential cellular components, yet exhibit extensive copy number (CN) variation within and between species. CN might be partly determined by the requirement of dosage b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gibbons, John G., Branco, Alan T., Godinho, Susana A., Yu, Shoukai, Lemos, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345604/
https://ncbi.nlm.nih.gov/pubmed/25583482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416878112
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