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Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates
Since its discovery and isolation, exogenous insulin has dramatically changed the outlook for patients with diabetes. However, even when patients strictly follow an insulin regimen, serious complications can result as patients experience both hyperglycemic and hypoglycemic states. Several chemically...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345600/ https://ncbi.nlm.nih.gov/pubmed/25675515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424684112 |
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