Supramolecular PEGylation of biopharmaceuticals

The covalent modification of therapeutic biomolecules has been broadly explored, leading to a number of clinically approved modified protein drugs. These modifications are typically intended to address challenges arising in biopharmaceutical practice by promoting improved stability and shelf life of...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Webber, Matthew J., Appel, Eric A., Vinciguerra, Brittany, Cortinas, Abel B., Thapa, Lavanya S., Jhunjhunwala, Siddharth, Isaacs, Lyle, Langer, Robert, Anderson, Daniel G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167179/
https://ncbi.nlm.nih.gov/pubmed/27911829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616639113
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