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A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling

Tissue and extracellular matrix (ECM) stiffness is transduced into intracellular stiffness, signaling, and changes in cellular behavior. Integrins and several of their associated focal adhesion proteins have been implicated in sensing ECM stiffness. We investigated how an initial sensing event is tr...

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Bibliografiska uppgifter
I publikationen:Sci Signal
Huvudupphovsmän: Bae, Yong Ho, Mui, Keeley L., Hsu, Bernadette Y., Liu, Shu-Lin, Cretu, Alexandra, Razinia, Ziba, Xu, Tina, Puré, Ellen, Assoian, Richard K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345117/
https://ncbi.nlm.nih.gov/pubmed/24939893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004838
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