Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho

Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation correlate with stiffness of the arterial extracellular matrix (ECM), but causal relationships remain unclear. We show that VSMC plasticity is mech...

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Vydáno v:Cell Rep
Hlavní autoři: Talwar, Shefali, Kant, Aayush, Xu, Tina, Shenoy, Vivek B., Assoian, Richard K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142933/
https://ncbi.nlm.nih.gov/pubmed/33882318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109019
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