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Differential Activation of ERK and Rac Mediates the Proliferative and Anti-proliferative Effects of Hyaluronan and CD44

Hyaluronan, a widely distributed component of the extracellular matrix, exists in a high molecular weight (native) form and lower molecular weight form (HMW- and LMW-HA, respectively). These different forms of hyaluronan bind to CD44 but elicit distinct effects on cellular function. A striking examp...

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Hlavní autoři: Kothapalli, Devashish, Flowers, James, Xu, Tina, Puré, Ellen, Assoian, Richard K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581577/
https://ncbi.nlm.nih.gov/pubmed/18806267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802934200
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