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Joint Requirement for Rac and ERK Activities Underlies the Mid-G1 Phase Induction of Cyclin D1 and S Phase Entry in Both Epithelial and Mesenchymal Cells

Cyclin D1 gene induction is a key event in G1 phase progression. Our previous studies indicated that signaling to cyclin D1 is cell type-dependent because the timing of cyclin D1 gene expression in MCF10A mammary epithelial cells and mesenchymal cells such as fibroblasts and vascular smooth muscle c...

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Detalhes bibliográficos
Main Authors: Klein, Eric A., Campbell, Latoya E., Kothapalli, Devashish, Fournier, Alaina K., Assoian, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576533/
https://ncbi.nlm.nih.gov/pubmed/18715870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804537200
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