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Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion

Integrin-mediated adhesion to substratum is required for cyclin D1 induction in mesenchymal cells, but we show here that the induction of cyclin D1 persists despite blockade of ECM-integrin signaling in MCF10A mammary epithelial cells. E-cadherin-mediated cell-cell adhesion also supports cyclin D1 i...

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Detalhes bibliográficos
Main Authors: Fournier, Alaina K., Campbell, Latoya E., Castagnino, Paola, Liu, Wendy F., Chung, Betty M., Weaver, Valerie M., Chen, Christopher S., Assoian, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662746/
https://ncbi.nlm.nih.gov/pubmed/18187454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.017012
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