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The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration
Rho GTPases play an essential role in regulating cell spreading, adhesion, and migration downstream of integrin engagement with the extracellular matrix. In this review, we focus on RhoA and Rac1—2 Rho GTPases that are required for efficient adhesion and migration—and describe how specific guanine n...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114617/ https://ncbi.nlm.nih.gov/pubmed/24607953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.27958 |
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