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N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells

In contrast to the accepted pro-proliferative effect of cell-matrix adhesion, the proliferative effect of cadherin-mediated cell-cell adhesion remains unresolved. Here, we studied the effect of N-cadherin on cell proliferation in the vasculature. We show that N-cadherin is induced in smooth muscle c...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mui, Keeley L., Bae, Yong Ho, Gao, Lin, Liu, Shu-Lin, Xu, Tina, Radice, Glenn L., Chen, Christopher S., Assoian, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560684/
https://ncbi.nlm.nih.gov/pubmed/25753414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.023
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