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Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators

OBJECTIVE: Vascular extracellular matrix (ECM) stiffening is a risk factor for aortic and coronary artery disease. How matrix stiffening regulates the transcriptome profile of human aortic (Ao) and coronary (Co) vascular smooth muscle cells (VSMCs) is not well understood. Furthermore, the role of lo...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Yu, Christopher, Xu, Tina, Assoian, Richard, Rader, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881588/
https://ncbi.nlm.nih.gov/pubmed/29051139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310237
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