Vascular Smooth Muscle Cell Stiffness as a Mechanism for Increased Aortic Stiffness with Aging

RATIONALE: Increased aortic stiffness, an important feature of many vascular diseases, e.g., aging, hypertension, atherosclerosis and aortic aneurysms, is assumed due to changes in extracellular matrix (ECM). OBJECTIVE: We tested the hypothesis that the mechanisms also involve intrinsic stiffening o...

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Autors principals: Qiu, Hongyu, Zhu, Yi, Sun, Zhe, Trzeciakowski, Jerome P., Gansner, Meredith, Depre, Christophe, Resuello, Ranillo R.G., Natividad, Filipinas F., Hunter, William C., Genin, Guy M., Elson, Elliot L., Vatner, Dorothy E., Meininger, Gerald A., Vatner, Stephen F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936100/
https://ncbi.nlm.nih.gov/pubmed/20634486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.221846
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