Vascular Smooth Muscle Cell Stiffness as a Mechanism for Increased Aortic Stiffness with Aging

RATIONALE: Increased aortic stiffness, an important feature of many vascular diseases, e.g., aging, hypertension, atherosclerosis and aortic aneurysms, is assumed due to changes in extracellular matrix (ECM). OBJECTIVE: We tested the hypothesis that the mechanisms also involve intrinsic stiffening o...

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Bibliografiske detaljer
Main Authors: Qiu, Hongyu, Zhu, Yi, Sun, Zhe, Trzeciakowski, Jerome P., Gansner, Meredith, Depre, Christophe, Resuello, Ranillo R.G., Natividad, Filipinas F., Hunter, William C., Genin, Guy M., Elson, Elliot L., Vatner, Dorothy E., Meininger, Gerald A., Vatner, Stephen F.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936100/
https://ncbi.nlm.nih.gov/pubmed/20634486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.221846
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