Mitochondrial Reprogramming Induced by CaMKIIδ Mediates Hypertrophy Decompensation

RATIONALE: Sustained activation of Gq signaling during pressure overload causes cardiac hypertrophy that ultimately progresses to dilated cardiomyopathy. The molecular events that drive hypertrophy decompensation are incompletely understood. Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKI...

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Publicado no:Circ Res
Main Authors: Westenbrink, B. Daan, Ling, Haiyun, Divakaruni, Ajit, Gray, Charles B. B., Zambon, Alexander C., Dalton, Nancy D., Peterson, Kirk L., Gu, Yusu, Matkovich, Scot J., Murphy, Anne, Miyamoto, Shigeki, Dorn, Gerald W., Brown, Joan Heller
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344921/
https://ncbi.nlm.nih.gov/pubmed/25605649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.304682
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