ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca(2+) Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ

ATPase inhibitory factor-1 (IF1) preserves cellular ATP under conditions of respiratory collapse, yet the function of IF1 under normal respiring conditions is unresolved. We tested the hypothesis that IF1 promotes mitochondrial dysfunction and pathological cardiomyocyte hypertrophy in the context of...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Pavez-Giani, Mario G., Sánchez-Aguilera, Pablo I., Bomer, Nils, Miyamoto, Shigeki, Booij, Harmen G., Giraldo, Paula, Oberdorf-Maass, Silke U., Nijholt, Kirsten T., Yurista, Salva R., Milting, Hendrik, van der Meer, Peter, de Boer, Rudolf A., Heller Brown, Joan, Sillje, Herman W. H., Westenbrink, B. Daan
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122940/
https://ncbi.nlm.nih.gov/pubmed/33922643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094427
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