ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca(2+) Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ

ATPase inhibitory factor-1 (IF1) preserves cellular ATP under conditions of respiratory collapse, yet the function of IF1 under normal respiring conditions is unresolved. We tested the hypothesis that IF1 promotes mitochondrial dysfunction and pathological cardiomyocyte hypertrophy in the context of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Pavez-Giani, Mario G., Sánchez-Aguilera, Pablo I., Bomer, Nils, Miyamoto, Shigeki, Booij, Harmen G., Giraldo, Paula, Oberdorf-Maass, Silke U., Nijholt, Kirsten T., Yurista, Salva R., Milting, Hendrik, van der Meer, Peter, de Boer, Rudolf A., Heller Brown, Joan, Sillje, Herman W. H., Westenbrink, B. Daan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122940/
https://ncbi.nlm.nih.gov/pubmed/33922643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094427
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