Emerging therapeutic paradigms to target the dysregulated JAK/STAT pathways in hematological malignancies

Over the past decade, there has been increasing biochemical evidence that the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway is aberrantly activated in malignant cells from patients with a wide spectrum of cancers of the blood and immune systems. The emerging avai...

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Библиографические подробности
Опубликовано в: :Leuk Lymphoma
Главные авторы: Mughal, Tariq I., Girnius, Saulius, Rosen, Steven T., Kumar, Shaji, Wiestner, Adrian, Abdel-Wahab, Omar, Kiladjian, Jean-Jacques, Wilson, Wyndham H., Van Etten, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344832/
https://ncbi.nlm.nih.gov/pubmed/24206094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.863307
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