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IL-10/Jak/Stat3 signaling dysregulates Bim expression in ALPS
BACKGROUND: Autoimmune lymphoproliferative syndrome (ALPS) is a human disorder of T cell homeostasis caused by mutations that impair Fas-mediated apoptosis. A defining characteristic of ALPS is the expansion of double negative T cells (DNTC). Relatively little is known about how defective Fas-driven...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Allergy Clin Immunol |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344440/ https://ncbi.nlm.nih.gov/pubmed/25174872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.07.020 |
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