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JAK/STAT pathway dysregulation in tumors: A Drosophila perspective

Sustained activation of the JAK/STAT pathway is causal to human cancers. This pathway is less complex in Drosophila, and its dysregulation has been linked to several tumor models in this organism. Here, we discuss models of metastatic epithelial and hematopoietic tumors that are causally linked to d...

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Hlavní autoři: Amoyel, Marc, Anderson, Abigail M., Bach, Erika A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037387/
https://ncbi.nlm.nih.gov/pubmed/24685611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.03.023
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