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JAK/STAT pathway dysregulation in tumors: A Drosophila perspective

Sustained activation of the JAK/STAT pathway is causal to human cancers. This pathway is less complex in Drosophila, and its dysregulation has been linked to several tumor models in this organism. Here, we discuss models of metastatic epithelial and hematopoietic tumors that are causally linked to d...

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Detalhes bibliográficos
Main Authors: Amoyel, Marc, Anderson, Abigail M., Bach, Erika A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037387/
https://ncbi.nlm.nih.gov/pubmed/24685611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.03.023
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