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JAK/STAT signaling is required for hinge growth and patterning in the Drosophila wing disc

JAK/STAT signaling is localized to the wing hinge, but its function is not known. Here we show that the Drosophila STAT Stat92E is downstream of Homothorax and is required for hinge development by cell-autonomously regulating hinge-specific factors. Within the hinge, Stat92E activity becomes restric...

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Bibliografiska uppgifter
Huvudupphovsmän: Ayala-Camargo, Aidee, Anderson, Abigail M., Amoyel, Marc, Rodrigues, Aloma B., Flaherty, Maria Sol, Bach, Erika A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795806/
https://ncbi.nlm.nih.gov/pubmed/23978534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.08.016
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