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JAK/STAT signaling is required for hinge growth and patterning in the Drosophila wing disc

JAK/STAT signaling is localized to the wing hinge, but its function is not known. Here we show that the Drosophila STAT Stat92E is downstream of Homothorax and is required for hinge development by cell-autonomously regulating hinge-specific factors. Within the hinge, Stat92E activity becomes restric...

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Detalhes bibliográficos
Main Authors: Ayala-Camargo, Aidee, Anderson, Abigail M., Amoyel, Marc, Rodrigues, Aloma B., Flaherty, Maria Sol, Bach, Erika A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795806/
https://ncbi.nlm.nih.gov/pubmed/23978534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.08.016
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