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Autonomous actions of the human growth hormone long-range enhancer

The human growth hormone (hGH) gene is controlled by a long-range enhancer, HSI, located 14.5 kb 5′ to the hGH promoter. HSI establishes a domain of noncoding transcription that is ‘looped’ to the hGH promoter as an essential step in initiating hGH gene expression. Thus, defining how HSI generates i...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Yoo, Eung Jae, Brown, Christopher D., Tsai, Yu-Cheng, Cooke, Nancy E., Liebhaber, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344525/
https://ncbi.nlm.nih.gov/pubmed/25662214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv093
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