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An RNA-Independent Linkage of Noncoding Transcription to Long-Range Enhancer Function

The detection of noncoding transcription at multiple enhancers within the mammalian genome raises critical questions regarding whether and how this activity contributes to enhancer function. Here, using in vivo analysis of a human growth hormone (hGH) transgene locus, we report that activation of a...

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書目詳細資料
Main Authors: Yoo, Eung Jae, Cooke, Nancy E., Liebhaber, Stephen A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347415/
https://ncbi.nlm.nih.gov/pubmed/22431516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06650-11
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