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An RNA-Independent Linkage of Noncoding Transcription to Long-Range Enhancer Function

The detection of noncoding transcription at multiple enhancers within the mammalian genome raises critical questions regarding whether and how this activity contributes to enhancer function. Here, using in vivo analysis of a human growth hormone (hGH) transgene locus, we report that activation of a...

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Detalhes bibliográficos
Main Authors: Yoo, Eung Jae, Cooke, Nancy E., Liebhaber, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347415/
https://ncbi.nlm.nih.gov/pubmed/22431516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06650-11
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