Single live cell TGF-β signalling imaging: breast cancer cell motility and migration is driven by sub-populations of cells with dynamic TGF-β-Smad3 activity

BACKGROUND: Metastasis is a process where only a small subset of cells is capable of successfully migrating to and propagating at secondary sites. TGF-β signalling is widely known for its role in cancer metastasis and is associated with cell migration in whole cell populations. FINDINGS: We extend t...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer
Hoofdauteurs: Luwor, Rodney B, Hakmana, Dulani, Iaria, Josephine, Nheu, Thao V, Simpson, Richard J, Zhu, Hong-Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343191/
https://ncbi.nlm.nih.gov/pubmed/25744371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0309-1
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