TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells

BACKGROUND: Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, with a 5-year survival rate of less than 8%. The complicated tumor microenvironment, particularly TGF-β, provides possible convenience for the progression of PC cells. TGF-β regulates critical cellular processes, inc...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: He, Ruizhi, Wang, Min, Zhao, Chunle, Shen, Ming, Yu, Yahong, He, Li, Zhao, Yan, Chen, Hua, Shi, Xiuhui, Zhou, Min, Pan, Shutao, Liu, Yuhui, Guo, Xingjun, Li, Xu, Qin, Renyi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683473/
https://ncbi.nlm.nih.gov/pubmed/31387632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1343-4
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