Regulatory B cells induced by pancreatic cancer cell-derived interleukin-18 promote immune tolerance via the PD-1/PD-L1 pathway

Dysregulation of regulatory B cells (Bregs), a type of immunosuppressive lymphocyte, are associated with development of autoimmune diseases and cancers. Bregs produce immune tolerance-inducing cell surface molecules and tolerogenic cytokines (interleukin [IL]-10 and transforming growth factor-beta)....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Yan, Shen, Ming, Feng, Yecheng, He, Ruizhi, Xu, Xiaodong, Xie, Yu, Shi, Xiuhui, Zhou, Min, Pan, Shutao, Wang, Min, Guo, Xingjun, Qin, Renyi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871079/
https://ncbi.nlm.nih.gov/pubmed/29599908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22976
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